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Our Solution

Just don’t let the fluids accumulate

Learn more about patient pain The Pain

Paragate Medical improves clinical condition of fluid overloaded patients by continuously removing extracellular fluids with a unique implantable peritoneal ultrafiltration device, operating non-aggressively and independently of the kidneys’ function.

The Paragate device breaks the hospitalization cycle for the chronic overloaded patients.


Instead of receiving acute, aggressive and costly diuresis or dialyses treatments that can’t prevent recurrence of the overload episodes,

The Paragate device offers 24/7 out-of-hospital solution to keep patients balanced at home.

Quick Breakeven
Quality Of Life
HF Exacerbation
Burden Of Care
Patient Engagement


Heart Failure

The #1 reason for repeated hospitalizations

Congestion (fluid overload) is a classic clinical symptom of heart failure (HF) patients, with diuretics being the gold standard treatment. However, of the ~26 million HF patients worldwide, 30-40% are diuretic resistant and about 50% of those are overloaded (“wet & warm”). Their only viable options are hospital-based interventions such as IV diuresis, ultrafiltration therapy, or peritoneal dialysis – all of which are costly, carry complications, and do not prevent recurrence of congestion and rehospitalizations.

Severe heart failure fills your lungs with fluid until you
can’t breathe.
Time and time again.

8.4 drop-icon=up

9 Out Of 10

HF Admissions


1-Month Readmissions


In US Alone
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dialysis patients

Dialysis treatments nowadays, too long, too cumbersome

too risky

Pathologic fluid overload is also a huge pain for Chronic Kidney (CKD) and End Stage Renal Disease (ESRD) patients. Inter-dialytic weight gain is a major cause of complications in hemodialysis (HD) treatment, including hemodynamic shock, arrhythmia and heart failure exacerbation. The tendency of dialysis patients to accumulate fluid must be managed through dietary limitations and ultrafiltration during dialysis sessions, both hindered by patient adherence, fluid status assessment and dialysis sessions duration. Achieving balance between chronic hypervolemia and acute hypotension remains a big challenge. Excessive ultrafiltration rates during HD sessions imply of higher morbidity and mortality, requiring HD to be carefully and slowly administered.


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